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Research and Development modalities – NGP Neuro

Research and Development modalities

The activities of the NGP are led by The Neuro and consist of distinct modules. The NGP Governance oversees the conduct of module activities.

Lead: Ziv Gan-Or
Co-leads: V.Mooser, G. Rouleau

 

Members and collaborators:

Takeda: Daria Prilutsky
Roche: Dheeraj Malhotra
Illumina: Caitlin Taylor

 

Phase 1 – Aim: Perform a comprehensive genetic analysis involving whole genome sequencing (WGS) in iRBD patients to help identify rapid converters and stratify them for enrolment into future clinical trials.

Lead: Madeleine Sharp
Co-leads: R. Postuma, J. Doyon

 

Members:

Takeda: Jaya Padmanabhan
Roche: Thomas Kustermann

 

Phase 1 – Aim: Prospectively deeply phenotype a proportion of patients with idiopathic REM sleep behavior disorder (iRBD) as well as a comparable group of patients that have already manifested with PD and non-RBD controls.

Lead: Thomas Durcan
Co-leads: E. Fon

 

Members:

Takeda: Hans Schiffer
Roche: Ravi Jagasia

 

Phase 1 – Aim: Identify disease phenotypes in microglia of LRRK2 PD patients.